Revision as of 21:16, 9 June 2016

Comparing Two Models of HMPAO Uptake in the Lungs: Is a Compartmental Model Sufficient to Reliably Estimate Key Physiological Parameters?

Benchmarks

1. Become familiar with MatLab syntax by creating a Computed Tomography (CT) program

2. Create a Graphical User Interface (GUI) to simulate a CT scan

3. Create GUI to simulate forward model of a Single Photon Emission CT(SPECT) scan (with and without noise)

4. Improve SPECT GUI to estimate parameters of the SPECT forward model given the concentration of radioactive material put into the system and output of the noisy lung

5. Determine whether the parameters given by a compartmental model of HMPAO uptake in the lung are reliable

Weekly Log

Week 1 (5/31 - 6/3)

- Met with Dr. Clough

   - Discussed scope of project
   
   - Learned basics of CT, SPECT, and PET scans (projections, Radon transform, Inverse Radon transform, reconstruction)
  
   - Defined benchmarks for the summer

{ Next meeting Tuesday 6/7 with Dr. Clough and Graduate student(s)}

- Attended Dr. Factor's talk on basics of research

   - Using the tools you have
   
   - Thoughtful consideration of a problem and solutions
   
   - Know what you don't know ==> develop a strategy to figure it out
   
   - Find out what is already known (do you need a new algorithm?)
   
   - Break the problem down into manageable pieces
   
   - Know your audience
   

- Conducted background research on CT scans

   - How they have improved (greater efficiency and effectiveness)
   
   - Confirmed understanding of basics given by Dr. Clough
   

- Wrote preliminary MatLab programs

   - Created image to be scanned
   
   - Calculated projection image (Radon transform as well as individual projections)
   
   - Reconstructed image (Inverse radon transform)
   

- Researched basic GUI construction

For next week  : Begin constructing GUI for preliminary CT simulation

Week 2 (6/6 - 6/10)

Week 3 (6/13 - 6/17)

Week 4 (6/20 - 6/24)

Week 5 (6/27 - 7/1)

Week 6 (7/4 - 7/8)

Week 7 (7/11 - 7/15)

Week 8 (7/18 - 7/22)

Week 9 (7/25 - 7/29)

Week 10 (8/1 - 8/5)

Personal Information

Kim is studying Mathematics at Lindenwood University in Saint Charles, MO.